{"id":4100,"date":"2025-10-29T16:12:40","date_gmt":"2025-10-29T19:12:40","guid":{"rendered":"https:\/\/overticeportal.com.br\/?p=4100"},"modified":"2025-10-29T16:12:41","modified_gmt":"2025-10-29T19:12:41","slug":"vacina-contra-herpes-zoster-pode-ajudar-a-prevenir-demencia-indica-estudo","status":"publish","type":"post","link":"https:\/\/www.portalam9.com.br\/?p=4100","title":{"rendered":"Vacina contra herpes-z\u00f3ster pode ajudar a prevenir dem\u00eancia, indica estudo"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><em>Tempo de leitura: 2 minutos <\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A reativa\u00e7\u00e3o do v\u00edrus herpes-z\u00f3ster pode aumentar\u00a0 risco de desenvolver quadros de dem\u00eancia, como o Alzheimer, de acordo com um estudo recente publicado pela revista Nature Medicine. No entanto, a vacina\u00e7\u00e3o contra a doen\u00e7a pode reduzir esse risco, principalmente quando a pessoa recebe mais de uma dose do imunizante.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Causada pelo v\u00edrus varicela-zoster, o mesmo respons\u00e1vel pela catapora, a herpes-z\u00f3ster \u00e9 uma doen\u00e7a que se manifesta na pele, gerando erup\u00e7\u00f5es cut\u00e2neas que duram de duas a quatro semanas. Trata-se de uma inflama\u00e7\u00e3o viral nos nervos da pele, se manifestando por meio de les\u00f5es avermelhadas, doloridas e com bolhas.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A doen\u00e7a ocorre anos ap\u00f3s um quadro de\u00a0catapora, que, geralmente, ocorre na inf\u00e2ncia. Ap\u00f3s esse quadro, o v\u00edrus varicela-zoster costuma permanecer &#8220;dormente&#8221; por anos no corpo da pessoa, mas pode ser reativado em pessoas com o sistema imunol\u00f3gico enfraquecido, causando a herpes-z\u00f3ster.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Existem evid\u00eancias de que o v\u00edrus varicela-zoster tem papel em processos inflamat\u00f3rios ou degenerativos no c\u00e9rebro, mas ainda faltam estudos robustos sobre o tema. Diante disso, os pesquisadores queriam investigar, por meio de uma an\u00e1lise observacional, se h\u00e1 rela\u00e7\u00e3o entre o v\u00edrus da herpes-z\u00f3ster e o risco de desenvolver\u00a0dem\u00eancia\u00a0ao longo dos anos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Para isso, o estudo usou registros eletr\u00f4nicos de sa\u00fade de uma base chamada Optum EHR, que re\u00fane dados de cl\u00ednicas e hospitais nos Estados Unidos. No total, foram analisados dados de mais de 100 milh\u00f5es de pessoas acompanhadas entre 2007 e 2023, com 50 anos ou mais. Foram comparadas informa\u00e7\u00f5es de pessoas que tiveram herpes-z\u00f3ster, ou que tomaram a vacina contra a doen\u00e7a, com as de pessoas que n\u00e3o tiveram a doen\u00e7a ou nem tomaram o imunizante.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">O trabalho descobriu que pessoas que tiveram mais de um epis\u00f3dio de herpes-z\u00f3ster apresentaram um risco maior de dem\u00eancia em compara\u00e7\u00e3o com aquelas que tiveram s\u00f3 um quadro. O aumento estimado foi modesto, mas consistente: um risco 7% a 9% maior cerca de tr\u00eas a nove anos ap\u00f3s o segundo epis\u00f3dio.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Os pesquisadores observaram ainda que quem foi vacinado contra herpes-z\u00f3ster teve um risco de dem\u00eancia mais baixo do que pessoas no grupo que n\u00e3o tomaram a vacina protetora. Al\u00e9m disso, vacinar com mais doses (por exemplo duas ou mais doses da vacina recombinante) mostrou benef\u00edcio maior do que uma dose s\u00f3.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Os autores interpretam os resultados como fortes evid\u00eancias de que a reativa\u00e7\u00e3o do v\u00edrus varicela-zoster pode ser um fator modific\u00e1vel de risco para dem\u00eancia. No entanto, existem ressalvas: embora a rela\u00e7\u00e3o entre herpes-zoster e dem\u00eancia pare\u00e7a robusta, ainda n\u00e3o \u00e9 poss\u00edvel afirmar a causalidade definitiva. Por isso, mais estudos devem ser realizados para confirmar os achados.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Fonte: CNN Brasil <strong>\/ <\/strong>Foto: Freepik <\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tempo de leitura: 2 minutos A reativa\u00e7\u00e3o do v\u00edrus herpes-z\u00f3ster pode aumentar\u00a0 risco de desenvolver<\/p>\n","protected":false},"author":3,"featured_media":4101,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[51],"tags":[],"class_list":["post-4100","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Vacina contra herpes-z\u00f3ster pode ajudar a prevenir dem\u00eancia, indica estudo - Portal Amazonas 9<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/portalam9.com.br\/?p=4100\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vacina contra herpes-z\u00f3ster pode ajudar a prevenir dem\u00eancia, indica estudo - 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