{"id":3848,"date":"2025-09-27T16:46:00","date_gmt":"2025-09-27T19:46:00","guid":{"rendered":"https:\/\/overticeportal.com.br\/?p=3848"},"modified":"2025-09-27T16:46:28","modified_gmt":"2025-09-27T19:46:28","slug":"descoberta-sobre-neuronios-pode-revolucionar-tratamento-do-alzheimer","status":"publish","type":"post","link":"https:\/\/www.portalam9.com.br\/?p=3848","title":{"rendered":"Descoberta sobre neur\u00f4nios pode revolucionar tratamento do Alzheimer\u00a0"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><em>Tempo de leitura: 2 minutos <\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">O\u00a0Alzheimer\u00a0\u00e9 uma doen\u00e7a neurodegenerativa caracterizada pela perda gradual de fun\u00e7\u00f5es cognitivas, como mem\u00f3ria, linguagem e racioc\u00ednio. Al\u00e9m disso, ela est\u00e1 ligada a altera\u00e7\u00f5es comportamentais e de humor, afetando milh\u00f5es de pessoas em todo o mundo.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Apesar de diversos tratamentos dispon\u00edveis, ainda existem muitas d\u00favidas sobre esta que \u00e9 considerada a forma mais comum de dem\u00eancia. Um cen\u00e1rio que pode mudar a partir de um estudo que criou o mapa mais detalhado j\u00e1 feito do envelhecimento cerebral humano.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/img.odcdn.com.br\/wp-content\/uploads\/2024\/08\/alzheimer-tratamento-1024x682.jpg\" alt=\"alzheimer\" class=\"wp-image-948454\"\/><figcaption class=\"wp-element-caption\">Trabalho pode mudar o entendimento sobre a doen\u00e7a (Imagem: Roman Bodnarchuk\/Shuttersotck)<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-neuronios-nao-morrem\"><strong>Neur\u00f4nios n\u00e3o morrem<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Em pesquisa publicada na revista cient\u00edfica\u00a0<em>Nature<\/em>, cientistas analisaram mais de 360 mil c\u00e9lulas do c\u00f3rtex pr\u00e9-frontal, regi\u00e3o ligada \u00e0 mem\u00f3ria, aten\u00e7\u00e3o e tomada de decis\u00f5es, em c\u00e9rebros de pessoas de idades que v\u00e3o de rec\u00e9m-nascidos a centen\u00e1rios;<\/li>\n\n\n\n<li>At\u00e9 agora, a ci\u00eancia explicava o envelhecimento cerebral sobretudo por dois mecanismos: a perda de neur\u00f4nios ao longo da vida, o que reduziria a capacidade de processamento do c\u00e9rebro, e o ac\u00famulo de prote\u00ednas t\u00f3xicas, como beta-amiloide e tau, associadas a doen\u00e7as como Alzheimer;<\/li>\n\n\n\n<li>O novo trabalho, no entanto, revelou que a condi\u00e7\u00e3o n\u00e3o ocorre em fun\u00e7\u00e3o da perda de neur\u00f4nios, mas sim pela queda de efici\u00eancia dos genes que mant\u00eam essas c\u00e9lulas funcionando;<\/li>\n\n\n\n<li>Esse preju\u00edzo fica mais evidente ap\u00f3s os 40 anos de idade.<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/img.odcdn.com.br\/wp-content\/uploads\/2024\/08\/neuronios-1-1024x578.jpg\" alt=\"\" class=\"wp-image-953208\"\/><figcaption class=\"wp-element-caption\">Cientistas fizeram importante descoberta sobre os neur\u00f4nios (Imagem: Corona Borealis Studio\/Shutterstock)<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-importancia-das-descobertas\"><strong>Import\u00e2ncia das descobertas<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Segundo a equipe respons\u00e1vel pelo trabalho, as descobertas abrem novas possibilidades de tratamento contra a doen\u00e7a. Os pesquisadores afirmam que os resultados do estudo demonstram que os cuidados com o c\u00e9rebro precisam come\u00e7ar cedo, especialmente a partir dos 40 anos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Outro ponto \u00e9 a identifica\u00e7\u00e3o de novos alvos terap\u00eauticos. Ao mostrar que os genes de manuten\u00e7\u00e3o celular s\u00e3o os mais afetados pelo envelhecimento, o estudo indica que&nbsp;futuras drogas podem ser desenhadas para preservar ou restaurar a efici\u00eancia desse processo.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/img.odcdn.com.br\/wp-content\/uploads\/2024\/07\/exame-de-sangue-alzheimer-1024x576.jpg\" alt=\"exame de sangue alzheimer\" class=\"wp-image-943875\"\/><figcaption class=\"wp-element-caption\">Resultados do estudo abrem caminho para novas formas de diagn\u00f3stico do Alzheimer (Imagem: joel bubble ben\/Shutterstock)<br><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Os cientistas ainda observam que os resultados da pesquisa ajudam a explicar por que alguns indiv\u00edduos desenvolvem Alzheimer enquanto outros envelhecem sem apresentar um decl\u00ednio t\u00e3o acentuado.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Dessa forma, \u00e9 poss\u00edvel pensar em formas de diagn\u00f3sticos mais precoces, estrat\u00e9gias de acompanhamento personalizadas e, no futuro, terapias voltadas \u00e0 causa biol\u00f3gica do envelhecimento cerebral.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Fonte: Olhar Digital <strong>\/ <\/strong>Foto: Lightspring\/Shutterstock<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tempo de leitura: 2 minutos O\u00a0Alzheimer\u00a0\u00e9 uma doen\u00e7a neurodegenerativa caracterizada pela perda gradual de fun\u00e7\u00f5es<\/p>\n","protected":false},"author":3,"featured_media":3849,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[51],"tags":[],"class_list":["post-3848","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - 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