{"id":3575,"date":"2025-09-10T15:11:03","date_gmt":"2025-09-10T18:11:03","guid":{"rendered":"https:\/\/overticeportal.com.br\/?p=3575"},"modified":"2025-09-10T16:11:31","modified_gmt":"2025-09-10T19:11:31","slug":"medicamento-inedito-devolve-movimento-a-pacientes-com-lesao-na-medula","status":"publish","type":"post","link":"https:\/\/www.portalam9.com.br\/?p=3575","title":{"rendered":"Medicamento in\u00e9dito devolve movimento a pacientes com les\u00e3o na medula"},"content":{"rendered":"\n

Tempo de leitura: 2 minutos <\/em><\/p>\n\n\n\n

Um medicamento desenvolvido no Brasil se mostrou capaz de devolver movimento a pacientes que sofreram les\u00f5es na medula espinhal e ficaram parapl\u00e9gicos ou tetrapl\u00e9gicos. A polilaminina<\/strong> \u00e9 produzida pelo laborat\u00f3rio Crist\u00e1lia em parceria com a Universidade Federal do Rio de Janeiro (UFRJ), e representa uma esperan\u00e7a para restaura\u00e7\u00e3o de les\u00f5es medulares rec\u00e9m ocorridas.<\/p>\n\n\n\n

Traumatismos na medula interrompem a comunica\u00e7\u00e3o entre o c\u00e9rebro e o corpo, trazendo limita\u00e7\u00f5es severas como paraplegia (perda dos membros inferiores) ou tetraplegia (comprometimento dos movimentos do pesco\u00e7o para baixo). Essas les\u00f5es s\u00e3o frequentemente causadas por acidentes de tr\u00e2nsito, quedas ou mergulhos.<\/p>\n\n\n\n

Em estudos experimentais, cerca de 10 pacientes conseguiram recuperar os movimentos com o uso de polilaminina, entre eles um jovem de 31 anos que sofreu trauma por acidente de tr\u00e2nsito, uma mulher de 27 anos, que sofreu uma queda, e um homem de 33 anos, que sofreu les\u00e3o por arma de fogo.<\/p>\n\n\n\n

Agora, o laborat\u00f3rio Crist\u00e1lia aguarda autoriza\u00e7\u00e3o da Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria (Anvisa) para iniciar a fase 1 dos estudos, que envolver\u00e1 mais cinco pacientes, para atestar a efic\u00e1cia e seguran\u00e7a do tratamento. A etapa \u00e9 fundamental para que o medicamento fique dispon\u00edvel em hospitais brasileiros.<\/p>\n\n\n\n

Como o medicamento funciona?<\/h2>\n\n\n\n

A polilaminina \u00e9 uma prote\u00edna capaz de regenerar as c\u00e9lulas da medula, devolvendo parcial ou totalmente a mobilidade ap\u00f3s uma les\u00e3o. A subst\u00e2ncia \u00e9 produzida naturalmente pelo corpo no desenvolvimento do sistema nervoso e, segundo descoberta dos pesquisadores da UFRJ, pode ser obtida atrav\u00e9s da placenta humana.<\/p>\n\n\n\n

\n

“\u00c9 uma alternativa mais acess\u00edvel e segura do que as c\u00e9lulas-tronco. Nossos estudos est\u00e3o em est\u00e1gio mais avan\u00e7ado, pois as c\u00e9lulas-tronco possuem imprevisibilidade ap\u00f3s a aplica\u00e7\u00e3o”, afirma Tatiana Coelho Sampaio, bi\u00f3loga do Instituto de Ci\u00eancias Biom\u00e9dicas da UFRJ e l\u00edder do estudo.<\/p>\n<\/blockquote>\n\n\n\n

Os efeitos da polilaminina s\u00e3o mais expressivos quando a aplica\u00e7\u00e3o ocorre em at\u00e9 24 horas ap\u00f3s o trauma, mas h\u00e1 benef\u00edcios tamb\u00e9m em les\u00f5es mais antigas. O tratamento exige apenas uma dose, seguida de fisioterapia para reabilita\u00e7\u00e3o.<\/p>\n\n\n\n

\n

“Demonstramos, por meio de evid\u00eancias robustas, que o produto cumpre os requisitos para ser considerado medicamento e oferecer uma alternativa vi\u00e1vel para quem n\u00e3o possui outras op\u00e7\u00f5es de tratamento. Fornecemos ainda o produto fabricado para a continuidade dos estudos em novas aplica\u00e7\u00f5es”, afirma Rog\u00e9rio Almeida, vice-presidente de P&D do Crist\u00e1lia.<\/p>\n<\/blockquote>\n\n\n\n

A pr\u00f3xima fase do estudo contar\u00e1 com a parceria do Hospital das Cl\u00ednicas da Universidade de S\u00e3o Paulo (USP) para as cirurgias e da AACD para o tratamento da reabilita\u00e7\u00e3o.<\/p>\n\n\n\n

Fonte: CNN Brasil \/ <\/strong>Foto: Huntstock\/GettyImages<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

A polilaminina representa uma esperan\u00e7a para a recupera\u00e7\u00e3o de pessoas que ficaram parapl\u00e9gicas ou tetrapl\u00e9gicas ap\u00f3s acidentes ou quedas<\/p>\n","protected":false},"author":3,"featured_media":3576,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[51],"tags":[],"class_list":["post-3575","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"yoast_head":"\nMedicamento in\u00e9dito devolve movimento a pacientes com les\u00e3o na medula - Portal Amazonas 9<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/portalam9.com.br\/?p=3575\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Medicamento in\u00e9dito devolve movimento a pacientes com les\u00e3o na medula - 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